Medicine uses for

 

Medicinal Uses

Phenindamine is used for treatment of:

  • Allergies
  • Hay fever
  • Common cold
  • Watery eyes
  • Runny nose
  • Sneezing

 

Side Effects

Side effects of Phenindamine are:

  • Fatigue
  • Dizziness
  • Drowsiness
  • Sleepiness
  • Dry mouth
  • Enlarged prostate
  • Difficulty in urination
  • Headache
  • Difficulty breathing
  • Closing of throat
  • Swellings in face

 

MCQs

Q.1 Match the following with correct SAR of the alkylamines antihistamine drugs:

i. E-isomers areA. More potent than Z-isomers
ii. S-enantiomers haveB. Less potent than Z-isomers
 C. Greater affinity for H1-receptors
 D. Greater affinity for H2-receptors
  1. i-A, ii-C
  2. i-A, ii-D
  3. i-B, ii-C
  4. i-B, ii-D

Q.2 Correct sequence for the True/False for correct IUPAC names of the drug can be?

  • Phenindamine: 2-methyl-9-phenyl-2,3,4,9-tetrahydro-1H-indeno[2,1-c]pyridine
  •  Diphenhydramine: 2-(diphenylmethoxy)-N,N-dimethylethanamine
  •  Auranofin: gold(1+);3,4,5-triacetyloxy-6-(acetyloxymethyl)oxane-2-thiolate;triethylphosphanium
  •  Meloxicam: 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ6,2-benzothiazine-3-carboxamide

a) TFFT

b) FFTF

c) TTTT

d) FFFT

Q.3 Molecular weight of Phenindamine is?

a) 200.5 gm/mol

b) 540.6 gm/mol

c) 261.4 gm/mol

d) 1042 gm/mol

Q.4 Phenindamine binds with which receptor to produce antihistaminic actions?

a) α-receptors

b) ß-receptors

c) Nicotinic receptor

d) H1-receptor

Q.5 Which amongst the following is not a therapeutic use of drug phenindamine?

a) Runny nose

b) Sneezing

c) Hay fever

d) Hypertension

Q.6 Which of the following drug and their classification are correct?

I. Phenindamine: H1 receptor antihistamine drug

II. Cimetidine: H2 receptor antihistamine drug

III. Lansoprazole: Proton pump inhibitor

IV. Thiotepa: Antineoplastic drug

a) I, III

b) I, II, III, IV

c) III, IV

d) I, II, IV

Q.7 Number of chiral centers present in the structure of phenindamine is?

a) 0

b) 1

c) 2

d) 3

 

 

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ANSWERS

1-a

2-c

3-c

4-d

5-d

6-b

7-b


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