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Anticholinergic Drugs

(Muscarinic receptor antagonists, Parasympatholytic, Atropinic)

Natural alkaloids

  • Atropine,
  • Hyoscine (Scopolamine).

Semisynthetic derivatives

  • Homatropine,
  •  Atropine
  •  methonitrate,
  • Hyoscine butyl bromide,
  • Ipratropium bromide,
  • Tiotropium bromide.

Synthetic compounds

(a)Mydriatics:

  • Cyclopentolate,
  • Tropicamide

 (b)Antisecretory-antispasmodics:

(i) Quaternary compounds:
  • Propantheline,
  • Oxyphenonium,
  • Clidinium,
  • Pipenzolate methylbromide,
  • Isopropamide,
  • Glycopyrrolate.
(ii) Tertiary amines:
  • Dicyclomine,
  • Valethamate,
  • Pirenzepine.

(c) Vasicoselective:

  • Oxybutynin,
  • Flavoxate,
  • Tolterodine.

(d)Antiparkinsonian:

  • Trihexyphenidyl (Benzhexol),
  • Procyclidine,
  • Biperiden.

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