 Tablet is defined as a compressed solid
dosage form containing medicaments with
or without excipients. According to the
...Advantages of Tablet Dosage Form
 Production aspect
 Large scale production atLarge scale production at
lowest costlowes...Disadvantages of Tablet
 Difficult to swallow in case of children and
unconscious patients.
 Some drugs resist compressi...Different Types of tablets
(A) Tablets ingested orally:
1. Compressed tablet, e.g. Paracetamol tablet
2. Multiple compress...(c) Tablets administered by other route:
1. Implantation tablet
2. Vaginal tablet, e.g. Clotrimazole tablet
(D) Tablets us...Tablet Ingredients
In addition to active ingredients, tablet
contains a number of inert materials known
as additives or ex...EXCIEPIENTS- functions
 Improve solubility
 Increase stability
 Impart weight, accuracy, & volume(its
allow accuracy of...A. DILUENTS
Diluents increase the volume to a formulation to
prepare tablets of the desired size. Widely used
fillers are ...Properties of Diluents
1. They must be non toxic.
2. They must be commercially available in
acceptable grade
3. There cost...B.BINDERS
 Binders promote the adhesion of particles of the
formulation. Such adhesion enables preparation of
granules an...Examples of Binders
Carboxymethylcellulose, sodium Karaya gum
Cellulose,microcrystalline(Avicel®) Starch, pregelatinized
E...C. Disintegrates
Added to a tablet formulation to facilitate its breaking
or disintegration when it contact in water in th...D. LUBRICANTS
 Lubricant is a substance capable of reducing or
preventing friction, heat, and wear when introduced as a
f... 1. Lubricants improve the flow of granules in the hopper
to the die cavity.
 2. Lubricants prevent sticking of tablet f... Commonly used lubricants include: talc,
magnesium stearat, calcium stearate
,stearic acid, hydrogenated vegetable oils
a...E. WETTING AGENTS
 Water molecules attract each other equally in all directions. Water
molecules on the surface, however,...

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