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 system is conventionally divided into the central nervous system (CNS; the brain and spinal cord) and the peripheral nervous system (PNS; neuronal tissues outside the CNS). Introduction to Autonomic Pharmacology The nervous system is conventionally divided into the central nervous system (CNS; the brain and spinal cord) and the periph-eral nervous system (PNS; neuronal tissues outside the CNS). The motor (efferent) portion of the nervous system can be divided into two major subdivisions: autonomic and somatic. The  autonomic nervous system (ANS)  is largely independent (autonomous) in that its activities are not under direct conscious control. It is concerned primarily with visceral functions such as cardiac output, blood flow to various organs, and digestion, which are necessary for life. Evidence is accumulating that the ANS, especially the vagus nerve, also influences immune func-tion and some CNS functions such as seizure discharge. The  somatic subdivi...
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Toggle navigation BrainKart.com         Home  |  SCIENCE  |  Pharmacology  -  |  Bioavailability - Pharmacokinetics  Previous Page Next Page  Chapter:  Basic & Clinical Pharmacology - Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail Bioavailability - Pharmacokinetics Bioavailability is defined as the fraction of unchanged drug reach-ing the systemic circulation following administration by any route . Bioavailability Bioavailability is defined as the fraction of unchanged drug reach-ing the systemic circulation following administration by any route (Table 3–3). The area under the blood concentration-time curve (AUC) is proportional to the extent of bioavailability for a drug if its elimination is first-o...
Adrenal hormones and synthetic substitutes fludrocortisone   Tablet: 100 micrograms (acetate).  hydrocortisone   Tablet: 5 mg; 10 mg; 20 mg.  Androgens Complementary List  testosterone  Injection: 200 mg (enanthate) in 1‐ml ampoule.  Contraceptives Oral hormonal contraceptives ethinylestradiol + levonorgestrel   Tablet: 30 micrograms + 150 micrograms. ethinylestradiol +  norethisterone   Tablet: 35 micrograms + 1mg. levonorgestrel Tablet: 30 micrograms; 750 micrograms (pack of two); 1.5 mg.  Injectable hormonal contraceptives estradiol cypionate + medroxyprogesterone acetate Injection: 5 mg + 25 mg. medroxyprogesterone acetate  Depot injection: 150 mg/ml in 1‐ml vial.  norethisterone enantate  Oily solution: 200 mg/ml in 1‐ml ampoule.    Intrauterine devices copper‐containing device   Barrier methods condoms  diaphragms  Implantable contr...
amiloride  Tablet: 5 mg (hydrochloride).  furosemide Injection: 10 mg/ml in 2‐ml ampoule. Oral liquid: 20 mg/5 ml  [c] . Tablet: 10 mg  [c] ; 20 mg  [c] ; 40 mg. hydrochlorothiazide  Solid oral dosage form: 25 mg. mannitol  Injectable solution: 10%; 20%. spironolactone  Tablet: 25 mg.  Complementary List  [c]  hydrochlorothiazide  Tablet (scored): 25 mg.  mannitol  Injectable solution: 10%; 20%. spironolactone Oral liquid: 5 mg/5 ml; 10 mg/5 ml; 25 mg/5 ml. Tablet: 25 mg.
atracurium   Injection: 10 mg/ml (besylate). neostigmine  Injection: 500 micrograms in 1‐ml ampoule; 2.5 mg (metilsulfate) in 1‐ml ampoule. Tablet: 15 mg (bromide). suxamethonium Injection: 50 mg (chloride)/ml in 2‐ml ampoule. Powder for injection: (chloride), in vial. vecuronium [c]  Powder for injection: 10 mg (bromide) in vial.   Complementary List  pyridostigmine Injection: 1 mg in 1‐ml ampoule. Tablet: 60 mg (bromide). vecuronium  Powder for injection: 10 mg (bromide) in vial. 
ascorbic acid  Tablet: 50 mg. calcium  Tablet: 500 mg (elemental).  cholecalciferol*  [c] Oral liquid: 400 IU/ml. Solid oral dosage form: 400 IU; 1000 IU. *  Ergocalciferol can be used as an alternative. ergocalciferol Oral liquid: 250 micrograms/ml (10 000 IU/ml). Solid oral dosage form: 1.25 mg (50 000 IU). iodine  Capsule: 200mg. Iodized oil: 1 ml (480 mg iodine); 0.5 ml (240 mg iodine) in ampoule (oral or injectable); 0.57 ml (308 mg iodine) in dispenser bottle. nicotinamide Tablet: 50 mg. pyridoxine  Tablet: 25 mg (hydrochloride).  retinol Capsule: 50 000 IU; 100000 IU; 200 000 IU (as palmitate). Oral oily solution: 100 000 IU (as palmitate)/ml in multidose dispenser. Tablet (sugar‐coated): 10 000 IU (as palmitate). Water‐miscible injection: 100 000 IU (as palmitate) in 2‐ml ampoule. riboflavin  Tablet: 5 mg. sodium fluoride  In any appropriate topical formulation.  thiamine  Tablet: 50 m...
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Toggle navigation BrainKart.com                       Home  |  SCIENCE  |  Pharmacology  -  |  How drugs are administered  Previous Page Next Page  Chapter:  Clinical Pharmacology: Fundamentals of clinical pharmacology Study Material, Lecturing Notes, Assignment, Reference, Wiki description explanation, brief detail How drugs are administered A drug’s administration route influences the quantity given and the rate at which the drug is absorbed and distributed. These vari-ables affect the drug’s action and the patient’s response. How drugs are administered A drug’s administration route influences the quantity given and the rate at which the drug is absorbed and distributed. These vari-ables affect the drug’s action and the patient’s response. Routes of administration include: ·      ...